Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.45 |
| ▸ | CA1 | P00915 | 12/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530534 | 0.84 | PTGES2 (0.39) | CA2CA1CA9CA12CA6 | |
| SCHEMBL6532196 | 0.81 | LMNA (0.39) | CA2CA1CA12CA5A | |
| SCHEMBL6026235 | 0.79 | PTGES2 (0.37) | CA2PTGES2 | |
| SCHEMBL6025517 | 0.77 | KMT2A (0.44) | CA2CA1CA9 | |
| SCHEMBL6025780 | 0.76 | PTGES2 (0.39) | CA2CA1CA9CA12CA6 | |
| SCHEMBL3763309 | 0.69 | CA2 (0.60) | CA2CA1CA9CA12CA6 | |
| SCHEMBL6526600 | 0.69 | CA2 (0.53) | CA2CA1CA9CA12CA6 | |
| SCHEMBL4735838 | 0.68 | BCL2L1 (0.45) | CA2CA1CA9CA12CA6 | |
| SCHEMBL4711064 | 0.67 | PTGES2 (0.64) | CA2CA1CA9CA12CA6 | |
| SCHEMBL6530524 | 0.67 | KMT2A (0.41) | CA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |