Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025519 | 0.89 | KMT2A (0.49) | L3MBTL1CA2CA12CA9GAA | |
| SCHEMBL6026285 | 0.82 | KMT2A (0.47) | L3MBTL1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL6531285 | 0.82 | KMT2A (0.46) | L3MBTL1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL6025782 | 0.78 | GBA1 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2GAAKMT2A | |
| SCHEMBL9629229 | 0.74 | KMT2A (0.46) | ALDH1A1L3MBTL1CA2CA12CA9 | |
| SCHEMBL6026237 | 0.74 | CA1 (0.46) | ALDH1A1CA2GAAKMT2ACA1 | |
| SCHEMBL8438771 | 0.71 | KMT2A (0.53) | ALDH1A1L3MBTL1CA2CA12CA9 | |
| SCHEMBL6530533 | 0.69 | ALPL (0.39) | SMN1; SMN2LMNA | |
| SCHEMBL6470836 | 0.68 | KMT2A (0.56) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL14061940 | 0.67 | CA2 (0.69) | ALDH1A1L3MBTL1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |