Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 10/20 | 0.37 |
| ▸ | PPARG | P37231 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532248 | 1.00 | MME (0.41) | MMEACECPA1ACE2ALKBH1 | |
| SCHEMBL6533595 | 0.93 | MME (0.44) | MMEACECPA1ACE2ALKBH1 | |
| SCHEMBL6533602 | 0.93 | MME (0.44) | MMEACECPA1ACE2ALKBH1 | |
| SCHEMBL6532384 | 0.91 | PPARG (0.43) | MMEACECPA1ACE2ALKBH1 | |
| SCHEMBL6534036 | 0.89 | MAOB (0.42) | ALKBH1MAOBPPARAPPARG | |
| SCHEMBL6534033 | 0.89 | MAOB (0.42) | ALKBH1MAOBPPARAPPARG | |
| SCHEMBL6532687 | 0.85 | LTA4H (0.43) | MMEACECPA1ACE2PPARA | |
| SCHEMBL6532682 | 0.85 | LTA4H (0.43) | MMEACECPA1ACE2PPARA | |
| SCHEMBL6532332 | 0.85 | PTGS2 (0.41) | ALKBH1PPARAPPARGPTGS2MEN1 | |
| SCHEMBL6532337 | 0.85 | PTGS2 (0.41) | ALKBH1PPARAPPARGPTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |