Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 9/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 5/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532337 | 1.00 | PTGS2 (0.41) | PTGS2PPARGPPARAATMPPARD | |
| SCHEMBL6532510 | 0.93 | PTGS2 (0.40) | PTGS2PPARGPPARAATMPPARD | |
| SCHEMBL6532517 | 0.93 | PTGS2 (0.40) | PTGS2PPARGPPARAATMPPARD | |
| SCHEMBL6532687 | 0.90 | LTA4H (0.43) | PPARGPPARAATMPPARDACACB | |
| SCHEMBL6532682 | 0.90 | LTA4H (0.43) | PPARGPPARAATMPPARDACACB | |
| SCHEMBL6533259 | 0.89 | PTGS2 (0.41) | PTGS2PPARGPPARAMEN1KMT2A | |
| SCHEMBL6533254 | 0.89 | PTGS2 (0.41) | PTGS2PPARGPPARAMEN1KMT2A | |
| SCHEMBL6532384 | 0.89 | PPARG (0.43) | PTGS2PPARGPPARAACACBMEN1 | |
| SCHEMBL6533887 | 0.86 | PPARG (0.39) | PPARGPPARAATMPPARDLTA4H | |
| SCHEMBL6533884 | 0.86 | PPARG (0.39) | PPARGPPARAATMPPARDLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |