SCHEMBL6532264

SCHEMBL6532264

CCCCCN1N=CCC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
MGLL Q99685 5/20 0.42
FAAH O00519 4/20 0.42
PTGS1 P23219 3/20 0.40
PTGS2 P35354 3/20 0.40
TP53 P04637 1/20 0.35
HSP90AA1 P07900 1/20 0.35
CYP3A4 P08684 1/20 0.35
G6PD P11413 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GBA1 P04062 1/20 0.35
KAT2B Q92831 1/20 0.34
CYP19A1 P11511 6/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27319400 0.94 GAA (0.43) ALDH1A1GAAMAPTTHRBMGLL
SCHEMBL10722393 0.86
SCHEMBL11500568 0.82 ALDH1A1 (0.47) ALDH1A1GAAMAPTTHRBMGLL
SCHEMBL11500561 0.75 ALDH1A1 (0.56) ALDH1A1GAAMAPTTHRBMGLL
SCHEMBL10722363 0.69
SCHEMBL1635324 0.68 ALDH1A1 (0.51) ALDH1A1GAAMAPTTHRBMGLL
SCHEMBL15064292 0.68 PDE4B (0.37) ALDH1A1GAAMAPTTHRBMGLL
SCHEMBL7607800 0.67 MGLL (0.44) ALDH1A1GAAMAPTTHRBMGLL
SCHEMBL2365151 0.67 ALDH1A1 (1.00) ALDH1A1GAAMAPTTHRBMGLL
SCHEMBL9153141 0.66 GAA (0.96) ALDH1A1GAAMAPTTHRBMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0720047-B1 Photographic element containing a stable aryloxypyrazolone coupler and process employing the same EASTMAN KODAK CO (US) 2002-07-03 EP claimed
EP-0720048-B1 Photographic element containing pyrazolone pug releasing coupler and imaging process employing same EASTMAN KODAK CO (US) 2001-10-24 EP claimed
US-5670306-A Photographic element containing pyrazolone pug releasing coupler and imaging process employing same EASTMAN KODAK COMPANY (US) 1997-09-23 US claimed
US-5576167-A Photographic element containing a stable aryloxypyrazolone coupler and process employing same EASTMAN KODAK COMPANY (US) 1996-11-19 US claimed
EP-0720048-A2 Photographic element containing pyrazolone pug releasing coupler and imaging process employing same EASTMAN KODAK COMPANY (US) 1996-07-03 EP claimed
EP-0720047-A2 Photographic element containing a stable aryloxypyrazolone coupler and process employing the same EASTMAN KODAK COMPANY (US) 1996-07-03 EP claimed
US-5405969-A Reacting a compound having a nucleophilic site with a thiol or disulfide in the presence of a base and an oxidizing agent EASTMAN KODAK COMPANY (US) 1995-04-11 US claimed
JP-8234386-A None JP disclosed
JP-8240891-A None JP disclosed
EP-0985538-B1 Ink jet printing process XEROX CORP (US) 2005-12-14 EP disclosed
US-6871945-B2 Ink jet printing process XEROX CORPORATION (US) 2005-03-29 US disclosed
US-20030160849-A1 Ink jet printing process XEROX CORPORATION 2003-08-28 US disclosed
US-6547380-B2 Ink jet printing process XEROX CORPORATION 2003-04-15 US disclosed
JP-H08240891-A PHOTOGRAPHIC ELEMENT EASTMAN KODAK CO 1996-09-17 JP disclosed
JP-H08234386-A PHOTOGRAPHIC ELEMENT EASTMAN KODAK CO 1996-09-13 JP disclosed
EP-0720048-A2 Photographic element containing pyrazolone pug releasing coupler and imaging process employing same EASTMAN KODAK COMPANY (US) 1996-07-03 EP disclosed
EP-0720048-A2 Photographic element containing pyrazolone pug releasing coupler and imaging process employing same EASTMAN KODAK COMPANY (US) 1996-07-03 EP disclosed
EP-0720047-A2 Photographic element containing a stable aryloxypyrazolone coupler and process employing the same EASTMAN KODAK COMPANY (US) 1996-07-03 EP disclosed
EP-0720047-A2 Photographic element containing a stable aryloxypyrazolone coupler and process employing the same EASTMAN KODAK COMPANY (US) 1996-07-03 EP disclosed
EP-0011693-A1 N-trifluoromethane-sulfonylaminophenyl-substituted N-heterocycles, their preparation, compositions containing them and their use in regulating plant growth CIBA-GEIGY AG (CH) 1980-06-11 EP disclosed