Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.50 |
| ▸ | MDH2 | P40926 | 3/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767714 | 0.90 | ALDH1A1 (0.53) | ALDH1A1MAPTNPC1ESR1LMNA | |
| SCHEMBL12658629 | 0.88 | SIRT2 (0.55) | ALDH1A1MAPTNPC1RAB9AESR1 | |
| SCHEMBL5333661 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MAPTNPC1RAB9AESR1 | |
| SCHEMBL5960040 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1ESR1LMNA | |
| SCHEMBL1994995 | 0.78 | ALDH1A1 (0.80) | ALDH1A1MAPTNPC1RAB9AESR1 | |
| SCHEMBL12658800 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL30316301 | 0.77 | NPC1 (0.64) | ALDH1A1MAPTNPC1RAB9AESR1 | |
| SCHEMBL9458998 | 0.77 | NPC1 (0.64) | ALDH1A1MAPTNPC1RAB9AESR1 | |
| SCHEMBL197446 | 0.77 | ALDH1A1 (0.83) | ALDH1A1MAPTNPC1RAB9AESR1 | |
| SCHEMBL10591672 | 0.77 | ALDH1A1 (0.83) | ALDH1A1MAPTNPC1RAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2319838-A1 | Therapeutic Molecules and Methods-1 | Cortical Pty Ltd (AU) | 2011-05-11 | — | — | EP | disclosed |
| US-20100323999-A1 | Therapeutic Molecules and Methods-1 | MORAND ERIC FRANCIS | 2010-12-23 | — | — | US | disclosed |
| US-20100323999-A1 | Therapeutic Molecules and Methods-1 | MORAND ERIC FRANCIS | 2010-12-23 | — | — | US | disclosed |
| US-7709514-B2 | Therapeutic molecules and methods-1 | CORTICAL PTY LTD (AU) | 2010-05-04 | — | — | US | disclosed |
| US-7709514-B2 | Therapeutic molecules and methods-1 | CORTICAL PTY LTD (AU) | 2010-05-04 | — | — | US | disclosed |
| WO-2005058304-A1 | IMPLANTABLE DEVICE CONTAINING INHIBITOR OF MACROPHAGE MIGRATION INHIBITORY FACTOR | CORTICAL PTY LTD (AU) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323999-A1 | Therapeutic Molecules and Methods-1 | MIF, IL1B, IL1A | GPR84 1444/4885ALDH1A1 329/4885MAPT 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.