Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 7/20 | 0.31 |
| ▸ | PPARA | Q07869 | 5/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534135 | 0.93 | PPARG (0.33) | ACACBPPARGPPARACTSLCTSK | |
| SCHEMBL6532684 | 0.83 | PPARG (0.38) | ACACBROCK2ROCK1LTA4HPPARG | |
| SCHEMBL6532718 | 0.82 | PPARG (0.43) | PPARGPPARA | |
| SCHEMBL6532377 | 0.76 | PPARG (0.39) | ROCK2ROCK1LTA4HPPARGPPARA | |
| SCHEMBL6532102 | 0.76 | PPARG (0.39) | ROCK2ROCK1LTA4HPPARGPPARA | |
| SCHEMBL6532609 | 0.76 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL6533025 | 0.76 | PPARG (0.40) | PPARGPPARAMAOB | |
| SCHEMBL6533825 | 0.76 | PPARG (0.37) | ROCK2LTA4HPPARGPPARA | |
| SCHEMBL6533257 | 0.76 | ROCK2 (0.34) | ROCK2PPARGPPARAMAOB | |
| SCHEMBL6532383 | 0.76 | PPARG (0.40) | ACACBROCK2ROCK1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |