Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532785 | 0.91 | RBP4 (0.40) | RBP4NPC1TSHRALDH1A1HTT | |
| SCHEMBL6532730 | 0.85 | JAK3 (0.37) | KMT2A | |
| SCHEMBL6530631 | 0.78 | MAPK1 (0.30) | — | |
| SCHEMBL6527893 | 0.77 | RBP4 (0.32) | RBP4 | |
| SCHEMBL6530861 | 0.77 | RBP4 (0.32) | RBP4 | |
| SCHEMBL6533971 | 0.76 | JAK3 (0.40) | GAAKMT2A | |
| SCHEMBL5623717 | 0.71 | NPC1 (0.40) | NPC1TSHRALDH1A1GAAKMT2A | |
| SCHEMBL6532434 | 0.71 | TYR (0.38) | RBP4HTTGAAKMT2A | |
| SCHEMBL6528273 | 0.69 | CDK7 (0.39) | — | |
| SCHEMBL6527385 | 0.69 | RBP4 (0.39) | RBP4TSHRALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |