Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532436 | 0.91 | RBP4 (0.37) | RBP4ALDH1A1POLBGAALMNA | |
| SCHEMBL6533971 | 0.85 | JAK3 (0.40) | GRM5GAAKMT2ASLC6A9GPR55 | |
| SCHEMBL5623717 | 0.81 | NPC1 (0.40) | ALDH1A1MAPTSMN1; SMN2POLBGAA | |
| SCHEMBL6527385 | 0.79 | RBP4 (0.39) | RBP4GRM5NPY2RALDH1A1MAPT | |
| SCHEMBL6527397 | 0.78 | MAPK1 (0.35) | GRM5NPY2RALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6532730 | 0.76 | JAK3 (0.37) | KMT2A | |
| SCHEMBL6532784 | 0.71 | RBP4 (0.41) | RBP4GRM5ALOX15HTTADRA1D | |
| SCHEMBL6528273 | 0.71 | CDK7 (0.39) | MAPT | |
| SCHEMBL6529978 | 0.70 | KMT2A (0.37) | NPY2RALDH1A1MAPTLMNAHPGD | |
| SCHEMBL6530631 | 0.69 | MAPK1 (0.30) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |