Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 4/20 | 0.31 |
| ▸ | RARG | P13631 | 4/20 | 0.31 |
| ▸ | RARA | P10276 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799937 | 0.77 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPTHTTRARB | |
| SCHEMBL6532504 | 0.75 | RARB (0.33) | RARBRARGRARARXRARXRB | |
| SCHEMBL132923 | 0.69 | MAPT (0.42) | ALDH1A1L3MBTL1MAPTHTTRARB | |
| SCHEMBL3978749 | 0.68 | TDP1 (0.41) | ALDH1A1L3MBTL1LMNACYP1A2CYP2D6 | |
| SCHEMBL28669863 | 0.67 | TP53 (0.38) | ALDH1A1L3MBTL1MAPTHTTRARB | |
| Cyclohexane SCHEMBL7643203 | 0.65 | RXRA (0.46) | ALDH1A1KMT2ARXRARXRBRXRG | |
| SCHEMBL5859592 | 0.65 | NR1H4 (0.35) | ALDH1A1L3MBTL1MAPTLMNACYP1A2 | |
| SCHEMBL17183990 | 0.65 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPTHTTRARB | |
| SCHEMBL10773147 | 0.65 | TDP1 (0.46) | ALDH1A1L3MBTL1MAPTHTTPDE4D | |
| SCHEMBL14677748 | 0.64 | MAPT (0.45) | ALDH1A1MAPTRARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6827325-B2 | Shape memory polymer or alloy ophthalmic lens mold and methods of forming ophthalmic products | JOHNSON & JOHNSON VISION CARE, INC. | 2004-12-07 | — | — | US | claimed |