Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139358 | 0.78 | MAPT (0.33) | MAPTGPR84FFAR1CA1 | |
| SCHEMBL8751663 | 0.74 | CA2 (0.39) | MAPTGPR84FFAR1ZDHHC20ZDHHC2 | |
| SCHEMBL27521083 | 0.67 | TSHR (0.39) | GPR84 | |
| SCHEMBL28146531 | 0.67 | TSHR (0.39) | GPR84 | |
| SCHEMBL27585313 | 0.67 | TSHR (0.39) | GPR84 | |
| SCHEMBL28051178 | 0.67 | TSHR (0.39) | GPR84 | |
| SCHEMBL5139759 | 0.67 | OPRM1 (0.35) | — | |
| SCHEMBL8735555 | 0.67 | ADH1C (0.40) | MAPTGPR84FFAR1ZDHHC20ZDHHC2 | |
| SCHEMBL5178163 | 0.67 | TSHR (0.38) | MAPTZDHHC20ZDHHC2CA1 | |
| SCHEMBL24322546 | 0.66 | PLA2G1B (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | claimed |
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |