Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 9/20 | 0.44 |
| ▸ | GAA | P10253 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569283 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8715905 | 0.70 | GAA (0.53) | KMT2AMEN1GAAMAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL1532118 | 0.70 | GAA (0.53) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL1876691 | 0.68 | NPC1 (0.63) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL22720444 | 0.68 | GAA (0.57) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL6533210 | 0.66 | MAPK1 (0.49) | KMT2AMEN1GAAMAPTALOX15 | |
| SCHEMBL28880139 | 0.65 | MAPK1 (0.61) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL5190975 | 0.65 | NPC1 (0.48) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL17047608 | 0.65 | RAB9A (0.64) | GAAALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL2692922 | 0.65 | CISD1 (0.54) | ALDH1A1KDM4EALOX15HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |