Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21532933 | 0.81 | PARP1 (0.54) | MAPK1RAB9ANPC1GAAHTT | |
| SCHEMBL6928574 | 0.72 | MEN1 (0.56) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL569283 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8715905 | 0.70 | GAA (0.53) | MAPK1RAB9ANPC1GAAHTT | |
| Ammonia Solution, Strong SCHEMBL1532118 | 0.70 | GAA (0.53) | MAPK1RAB9ANPC1GAAHTT | |
| SCHEMBL22720444 | 0.68 | GAA (0.57) | MAPK1RAB9ANPC1GAAHTT | |
| SCHEMBL6532742 | 0.66 | NR3C1 (0.44) | MAPK1RAB9ANPC1GAAHTT | |
| SCHEMBL7195570 | 0.65 | KMT2A (0.55) | MAPK1RAB9ANPC1GAAHTT | |
| SCHEMBL9413728 | 0.65 | MEN1 (0.55) | RAB9AGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10351939 | 0.65 | METAP2 (0.58) | MAPK1RAB9ANPC1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |