Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.50 |
| ▸ | UCHL1 | P09936 | 5/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955775 | 0.83 | ALDH1A1 (0.60) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL4955786 | 0.83 | ALDH1A1 (0.60) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL28975838 | 0.82 | GPR119 (0.54) | USP30ALDH1A1GPR119 | |
| SCHEMBL6532914 | 0.81 | DPP4 (0.42) | USP30UCHL1ALDH1A1GPR119 | |
| SCHEMBL6532310 | 0.81 | NPSR1 (0.49) | USP30UCHL1KLK7EPHX2NPC1 | |
| SCHEMBL6529896 | 0.81 | DPP4 (0.59) | UCHL1KLK7EPHX2NPC1MEN1 | |
| SCHEMBL6529986 | 0.81 | DPP4 (0.57) | NPC1 | |
| SCHEMBL6530105 | 0.80 | DPP4 (0.60) | USP30UCHL1KLK7EPHX2NPC1 | |
| SCHEMBL6530405 | 0.80 | DPP4 (0.60) | USP30UCHL1KLK7EPHX2NPC1 | |
| SCHEMBL3530509 | 0.79 | NPC1 (0.57) | USP30UCHL1KLK7EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |