Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529896 | 0.81 | DPP4 (0.59) | NPSR1LMNAALDH1A1GAATSHR | |
| SCHEMBL6532752 | 0.81 | USP30 (0.50) | NPSR1LMNAALDH1A1TSHRHSD17B10 | |
| SCHEMBL6530486 | 0.79 | DPP4 (0.71) | LMNADPP4DPP8DPP7SMN1; SMN2 | |
| SCHEMBL6530405 | 0.78 | DPP4 (0.60) | NPSR1LMNAALDH1A1GAATSHR | |
| SCHEMBL6530105 | 0.78 | DPP4 (0.60) | NPSR1LMNAALDH1A1GAATSHR | |
| SCHEMBL6533469 | 0.77 | HSD17B10 (0.44) | NPSR1LMNAALDH1A1GAATSHR | |
| SCHEMBL6532846 | 0.76 | ALDH1A1 (0.50) | NPSR1LMNAALDH1A1GAATSHR | |
| SCHEMBL6532278 | 0.75 | PKM (0.52) | NPSR1LMNAALDH1A1GAATSHR | |
| SCHEMBL6530822 | 0.74 | DPP4 (0.51) | NPSR1LMNAALDH1A1GAATSHR | |
| SCHEMBL6532350 | 0.74 | HCRTR1 (0.37) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |