Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.60 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23805529 | 0.83 | SIGMAR1 (0.82) | SIGMAR1POLBL3MBTL3 | |
| SCHEMBL16704827 | 0.83 | HIF1A (0.82) | HIF1AEPAS1KDM4EALDH1A1MAPT | |
| SCHEMBL6510417 | 0.81 | SIGMAR1 (0.58) | SIGMAR1POLBKDM4EALDH1A1CYP3A4 | |
| SCHEMBL18164592 | 0.80 | SIGMAR1 (0.54) | SIGMAR1ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL5450696 | 0.80 | KCNH2 (0.55) | SIGMAR1ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL2090287 | 0.80 | ALDH1A1 (0.47) | SIGMAR1ADRA1DADRA1AADRA1BL3MBTL3 | |
| SCHEMBL23805531 | 0.80 | SIGMAR1 (0.76) | SIGMAR1POLBL3MBTL3 | |
| Hydrochloric Acid SCHEMBL30152527 | 0.79 | KCNH2 (0.54) | SIGMAR1ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL18161375 | 0.78 | ADRA1D (0.48) | SIGMAR1ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL24351544 | 0.77 | SIGMAR1 (0.70) | SIGMAR1CD274POLBL3MBTL3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005077885-A1 | RUTHENIUM-CATALYZED HYDROAMINATION OF OLEFINS | YALE UNIVERSITY (US) | 2005-08-25 | — | — | WO | disclosed |