Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 15/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 13/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532686 | 0.84 | NPBWR1 (0.54) | NPBWR1MCHR1DRD2DRD4DRD3 | |
| SCHEMBL5904813 | 0.80 | SMO (0.57) | DRD2DRD4DRD3SMOP2RX7 | |
| SCHEMBL10176262 | 0.77 | SMO (0.55) | NPBWR1MCHR1DRD2DRD4DRD3 | |
| SCHEMBL22924531 | 0.77 | NPBWR1 (0.44) | NPBWR1MCHR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20712771 | 0.76 | NPBWR1 (0.46) | NPBWR1MCHR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8470679 | 0.71 | NOTUM (0.54) | DRD2DRD4DRD3SMOP2RX7 | |
| SCHEMBL15167628 | 0.71 | MAPK1 (0.55) | NPBWR1MCHR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6533834 | 0.70 | NPBWR1 (0.52) | NPBWR1MCHR1ALDH1A1CYP2C9 | |
| SCHEMBL27497189 | 0.69 | NPBWR1 (0.49) | NPBWR1MCHR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4544365 | 0.68 | SMN1; SMN2 (0.49) | NPBWR1MCHR1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |