Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 17/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 14/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532686 | 0.82 | NPBWR1 (0.54) | NPBWR1MCHR1NPC1ALDH1A1CYP1A2 | |
| SCHEMBL6534028 | 0.81 | NR4A3 (0.65) | NR4A3NPC1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL26042 | 0.70 | NR4A3 (0.54) | NR4A3ALDH1A1RAB9A | |
| SCHEMBL6532967 | 0.70 | NPBWR1 (0.44) | NPBWR1MCHR1ALDH1A1CYP2C9 | |
| SCHEMBL12338161 | 0.69 | NR4A3 (0.66) | NR4A3NPC1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL27497189 | 0.67 | NPBWR1 (0.49) | NPBWR1MCHR1NPC1ALDH1A1CYP1A2 | |
| SCHEMBL1567787 | 0.67 | NPBWR1 (0.60) | NPBWR1MCHR1NPC1ALDH1A1RAB9A | |
| SCHEMBL12340468 | 0.66 | NR4A3 (0.56) | NR4A3NPC1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL8470679 | 0.66 | NOTUM (0.54) | NPC1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL1195233 | 0.66 | NR4A3 (0.49) | NR4A3NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |