Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | EPOR | P19235 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371178 | 1.00 | LTA4H (0.47) | LTA4HEPORLMNAL3MBTL1PPARA | |
| SCHEMBL3373968 | 0.89 | LMNA (0.47) | LTA4HEPORLMNAL3MBTL1PPARA | |
| SCHEMBL6906563 | 0.89 | FFAR1 (0.49) | LTA4HEPORLMNAL3MBTL1PPARA | |
| SCHEMBL3373966 | 0.89 | LMNA (0.47) | LTA4HEPORLMNAL3MBTL1PPARA | |
| SCHEMBL3372345 | 0.89 | FFAR1 (0.49) | LTA4HEPORLMNAL3MBTL1PPARA | |
| SCHEMBL3369977 | 0.89 | LMNA (0.47) | LTA4HEPORLMNAL3MBTL1PPARA | |
| SCHEMBL3369824 | 0.88 | FFAR1 (0.50) | LTA4HEPORLMNAL3MBTL1PPARA | |
| SCHEMBL5024641 | 0.88 | FFAR1 (0.50) | LTA4HEPORLMNAL3MBTL1PPARA | |
| SCHEMBL3370006 | 0.88 | FFAR1 (0.51) | LTA4HEPORLMNAL3MBTL1PPARA | |
| SCHEMBL5024649 | 0.88 | FFAR1 (0.50) | LTA4HEPORLMNAL3MBTL1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551814-A1 | CHIRALE OXAZOLE-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004031162-A1 | CHIRALE OXAZOLE-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-04-15 | — | — | WO | disclosed |