Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | EPOR | P19235 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372345 | 1.00 | FFAR1 (0.49) | FFAR1LTA4HPPARDEPORLMNA | |
| SCHEMBL3373966 | 0.89 | LMNA (0.47) | FFAR1LTA4HPPARDEPORLMNA | |
| SCHEMBL3371178 | 0.89 | LTA4H (0.47) | FFAR1LTA4HPPARDEPORLMNA | |
| SCHEMBL6533050 | 0.89 | LTA4H (0.47) | FFAR1LTA4HPPARDEPORLMNA | |
| SCHEMBL3369977 | 0.89 | LMNA (0.47) | FFAR1LTA4HPPARDEPORLMNA | |
| SCHEMBL3373968 | 0.89 | LMNA (0.47) | FFAR1LTA4HPPARDEPORLMNA | |
| SCHEMBL3370006 | 0.88 | FFAR1 (0.51) | FFAR1LTA4HPPARDEPORLMNA | |
| SCHEMBL3369824 | 0.88 | FFAR1 (0.50) | FFAR1LTA4HPPARDEPORLMNA | |
| SCHEMBL5024641 | 0.88 | FFAR1 (0.50) | FFAR1LTA4HPPARDEPORLMNA | |
| SCHEMBL5024649 | 0.88 | FFAR1 (0.50) | FFAR1LTA4HPPARDEPORLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110807-A1 | Thiazole derivatives | HOFFMANN-LA ROCHE INC. | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110807-A1 | Thiazole derivatives | SLC5A1, GPR119, INSR | FFAR1 32/4885LTA4H 3280/4885PPARD 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.