Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.83 |
| ▸ | MEN1 | O00255 | 5/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 1/20 | 0.83 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523842 | 0.91 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9257004 | 0.78 | ALDH1A1 (0.76) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8154947 | 0.78 | CYP19A1 (0.77) | P2RX4CYP19A1HDAC1HDAC6 | |
| SCHEMBL9270554 | 0.77 | ALDH1A1 (0.74) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9272108 | 0.77 | ALDH1A1 (0.74) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8358470 | 0.76 | KMT2A (0.72) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11826856 | 0.76 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9535544 | 0.75 | KDM4E (1.00) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14692035 | 0.75 | ALDH1A1 (0.70) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11828707 | 0.74 | ALDH1A1 (0.70) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005520797-A | — | — | 2005-07-14 | — | — | JP | claimed |
| EP-1458718-A1 | QUINOLINONES AS PROSTAGLANDIN RECEPTOR LIGANDS | Merck Frosst Canada & Co. (CA) | 2004-09-22 | — | — | EP | claimed |
| WO-2003051878-A1 | QUINOLINONES AS PROSTAGLANDIN RECEPTOR LIGANDS | MERCK FROSST CANADA & CO. (CA) | 2003-06-26 | — | — | WO | claimed |