Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462175 | 0.87 | ALDH1A1 (0.83) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1790843 | 0.84 | ALDH1A1 (1.00) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9254043 | 0.82 | ALDH1A1 (0.89) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9262842 | 0.82 | ALDH1A1 (0.89) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30197876 | 0.82 | ALDH1A1 (0.89) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11828707 | 0.81 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17066941 | 0.81 | MEN1 (0.69) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30367071 | 0.81 | MEN1 (0.69) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11826856 | 0.80 | ALDH1A1 (0.68) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1523842 | 0.80 | ALDH1A1 (1.00) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041306-A | 4- hydroxyl -2- quinolone-nitrogen-(4- quinazolinone) -3- carboxamides derivatives | 中国医学科学院药物研究所 | 2019-07-23 | — | — | CN | disclosed |
| US-20180201583-A1 | QUINOLINONE OR QUINAZOLINONE COMPRISING ANTIBIOFILM COMPOSITIONS, COMPOUNDS AND METHODS AND USES RELATING THERETO | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND (IE) | 2018-07-19 | — | — | US | disclosed |
| US-5254595-A | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0375560-B1 | ARYLOXYPROPANOLAMINOTETRALINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ELF SANOFI (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0375560-A1 | Aryloxypropanolaminotetralines, process for their preparation and pharmaceutical compositions containing same | ELF SANOFI (FR) | 1990-06-27 | — | — | EP | disclosed |
| US-4874848-A | FOR DYEING WOOL, LEATHER, POLYAMIDES BLACK OR BROWN | CIBA-GEIGY CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| US-4661587-A | Bis 1:2 chromium complexes of disazo and azo or azomethine dyes | CIBA-GEIGY CORPORATION (US) | 1987-04-28 | — | — | US | disclosed |
| US-4652631-A | LEATHER, WOOL, POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| US-4650859-A | WOOL,POLYAMIDES, LEATHER | CIBA-GEIGY CORPORATION (US) | 1987-03-17 | — | — | US | disclosed |
| US-4563193-A | WOOL, POLYAMIDES, LEATHER | CIBA GEIGY CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |
| US-4502860-A | WOOL, POLYAMIDES, LEATHER | CIBA-GEIGY CORPORATION (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0012112-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | disclosed |
| US-4291901-A | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |
| EP-0012112-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |
| US-4101543-A | DYES FOR CELLULOSE ACETATES, AROMATIC POLYESTERS OR POLYAMIDES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180201583-A1 | QUINOLINONE OR QUINAZOLINONE COMPRISING ANTIBIOFILM COMPOSITIONS, COMPOUNDS AND METHODS AND USES RELATING THERETO | QSOX1, LPO, NQO2 | KDM4E 3548/4885ALDH1A1 544/4885MAPT 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.