Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270554 | 0.87 | ALDH1A1 (0.74) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1523842 | 0.86 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8358470 | 0.86 | KMT2A (0.72) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9259645 | 0.84 | MEN1 (0.65) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL14692035 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6533189 | 0.78 | ALDH1A1 (0.83) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9272108 | 0.78 | ALDH1A1 (0.74) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9161052 | 0.78 | KMT2A (0.52) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9158213 | 0.77 | MEN1 (0.72) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7723992 | 0.75 | SRC (0.53) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| US-5378694-A | Herpes viricide, hypotensive agent | SCHERING CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |