Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820590 | 0.84 | NOTUM (0.55) | EPHX2NOTUMMAPK1NPSR1GRM4 | |
| SCHEMBL9219459 | 0.80 | GABRB3 (0.57) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11900950 | 0.75 | NOTUM (0.49) | EPHX2NOTUMMAPK1NPSR1MEN1 | |
| SCHEMBL27339051 | 0.74 | POLB (0.46) | NPSR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25781179 | 0.73 | EPHX2 (0.42) | EPHX2ARNOTUMMAPK1NPSR1 | |
| SCHEMBL31517645 | 0.72 | SCD (0.34) | NOTUMMAPK1MEN1NPC1KMT2A | |
| SCHEMBL15180418 | 0.71 | DRD4 (0.52) | NOTUMMAPK1MEN1RAB9AKMT2A | |
| SCHEMBL15105019 | 0.71 | RXRA (0.48) | EPHX2KCNH2RXRAGRIN1GRIN2B | |
| SCHEMBL507896 | 0.71 | RXRA (0.44) | NOTUMMEN1NPC1RAB9AKMT2A | |
| SCHEMBL2412911 | 0.70 | GAA (0.58) | NOTUMMAPK1NPSR1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |