Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.40 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.39 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | LYN | P07948 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653323 | 1.00 | HSD11B1 (0.42) | HSD11B1MEN1KMT2APOLBPTPN7 | |
| SCHEMBL652083 | 0.89 | KMT2A (0.52) | HSD11B1MEN1KMT2APOLBPTPN7 | |
| SCHEMBL652084 | 0.89 | KMT2A (0.52) | HSD11B1MEN1KMT2APOLBPTPN7 | |
| SCHEMBL650340 | 0.85 | MAPT (0.45) | MEN1KMT2APOLBPTP4A3PIM1 | |
| SCHEMBL650341 | 0.85 | MAPT (0.45) | MEN1KMT2APOLBPTP4A3PIM1 | |
| SCHEMBL649045 | 0.84 | MEN1 (0.46) | MEN1KMT2APOLBPTPN7PTPN12 | |
| SCHEMBL649044 | 0.84 | MEN1 (0.46) | MEN1KMT2APOLBPTPN7PTPN12 | |
| SCHEMBL651164 | 0.83 | MAPT (0.52) | MEN1KMT2APOLBPTP4A3MAPT | |
| SCHEMBL651165 | 0.83 | MAPT (0.52) | MEN1KMT2APOLBPTP4A3MAPT | |
| SCHEMBL651383 | 0.83 | RNASEL (0.43) | MEN1KMT2APOLBPTP4A3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | CDC7, CDK17, CDCA2 | HSD11B1 972/4885MEN1 1406/4885KMT2A 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.