Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500566 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10ADORA1 | |
| SCHEMBL6470420 | 0.75 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10ADORA1 | |
| SCHEMBL6500282 | 0.68 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDHSD17B10ADORA1 | |
| SCHEMBL6498775 | 0.67 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL6506572 | 0.65 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10ADORA1 | |
| SCHEMBL6469895 | 0.65 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10ADORA1 | |
| SCHEMBL6470606 | 0.65 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDHSD17B10ADORA1 | |
| SCHEMBL1840091 | 0.64 | TSHR (0.53) | KDM4EALDH1A1HSD17B10MAPTGABRA2 | |
| SCHEMBL6504869 | 0.63 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10ADORA1 | |
| SCHEMBL7563411 | 0.62 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |