Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915463 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL6531802 | 0.88 | ADRB2 (0.49) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL6533340 | 0.85 | ADRB2 (0.49) | ADRB2POLB | |
| SCHEMBL6508632 | 0.85 | ADRB2 (0.49) | ADRB2ME2ME1ME3POLB | |
| SCHEMBL6529084 | 0.85 | ADRB2 (0.51) | ADRB2POLBKMT2AMEN1 | |
| SCHEMBL6482712 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL6509325 | 0.84 | ADRB2 (0.48) | ADRB2POLBKMT2AMEN1 | |
| SCHEMBL6506995 | 0.83 | ADRB2 (0.47) | L3MBTL1ADRB2POLB | |
| SCHEMBL6530357 | 0.82 | ADRB2 (0.47) | KDM4EL3MBTL1ADRB2POLBKMT2A | |
| SCHEMBL6503586 | 0.80 | ADRB2 (0.48) | ADRB2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |