Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 4/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533555 | 0.85 | ALDH1A1 (0.47) | CHRM5CHRM1CHRM3ALDH1A1LPAR1 | |
| SCHEMBL11225170 | 0.79 | CHRM5 (0.60) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10693309 | 0.77 | ALOX5 (0.58) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL10896138 | 0.75 | TP53 (0.43) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL4560242 | 0.75 | NPC1 (0.60) | CHRM5CHRM1CHRM3ALOX5LPAR1 | |
| SCHEMBL14443063 | 0.73 | LTB4R2 (0.50) | KMT2AMEN1ALDH1A1NPSR1NPC1 | |
| SCHEMBL10694993 | 0.73 | CHRM5 (0.54) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL6716281 | 0.73 | AOC3 (0.50) | CHRM1CHRM3CHRM2ALOX5ALDH1A1 | |
| SCHEMBL1581559 | 0.72 | CHRM5 (0.44) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL1581211 | 0.71 | ALDH1A1 (0.52) | CHRM5CHRM1CHRM3CHRM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042491-A1 | BENZAZEPINE DERIVATIVES AND METHODS OF PROPHYLAXIS OR TREATMENT OF 5HT2C RECEPTOR ASSOCIATED DISEASES | ARENA PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |