SCHEMBL653357

SCHEMBL653357

BrC(Br)(Br)C(Br)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.45
ALDH1A1 P00352 4/20 0.45
TSHR P16473 2/20 0.45
MAPK1 P28482 1/20 0.39
KIF11 P52732 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP1A2 P05177 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALOX15 P16050 1/20 0.36
PTPN1 P18031 1/20 0.35
ESR1 P03372 1/20 0.35
CYP3A4 P08684 1/20 0.35
ESR2 Q92731 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26697300 0.86 ALDH1A1 (0.50) KCNN4ALDH1A1TSHRMAPK1TDP1
SCHEMBL4812311 0.81 KCNN4 (0.41) KCNN4ALDH1A1TSHRMAPK1TDP1
SCHEMBL4815053 0.79 KCNN4 (0.39) KCNN4ALDH1A1TSHRMAPK1TDP1
SCHEMBL652269 0.79 KCNN4 (0.35) KCNN4ALDH1A1TSHRMAPK1KIF11
SCHEMBL652272 0.77 CA1 (0.38) KCNN4ALDH1A1TSHRMAPK1TDP1
SCHEMBL4812223 0.77 KCNN4 (0.38) KCNN4ALDH1A1TSHRMAPK1TDP1
SCHEMBL756427 0.73 KCNN4 (0.46) KCNN4ALDH1A1TSHRMAPK1TDP1
SCHEMBL1538898 0.72 ALDH1A1 (0.50) KCNN4ALDH1A1TSHRMAPK1TDP1
SCHEMBL21647231 0.72 ALDH1A1 (0.50) KCNN4ALDH1A1TSHRMAPK1TDP1
Bromotriphenylmethane SCHEMBL263 0.72 ALDH1A1 (0.50) KCNN4ALDH1A1TSHRMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118480235-A Ultralow-heat-conduction foamable material and preparation method thereof 天津格亚德新材料科技有限公司 2024-08-13 CN claimed
CN-109608976-B Temporary protection strippable coating with flame retardant property and preparation method thereof 中昊北方涂料工业研究设计院有限公司 2021-12-24 CN claimed
US-7977421-B2 Brominated diphenyl ethane mixtures and resin compositions including the same CHEIL INDUSTRIES INC. (KR) 2011-07-12 US claimed
US-20100029828-A1 Brominated Diphenyl Ethane Mixtures and Resin Compositions Including the Same CHEIL INDUSTRIES INC. (KR) 2010-02-04 US claimed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-5039729-A Consisting of hexabromodiphenyl ethane, heptabromodiphenyl ethane and octabromodiphenyl ethane; flame retarders ETHYL CORPORATION (US) 1991-08-13 US claimed
CN-118480235-A Ultralow-heat-conduction foamable material and preparation method thereof 天津格亚德新材料科技有限公司 2024-08-13 CN disclosed
CN-109608976-B Temporary protection strippable coating with flame retardant property and preparation method thereof 中昊北方涂料工业研究设计院有限公司 2021-12-24 CN disclosed
WO-2016078603-A1 AIE LUMINOGENS FOR BACTERIA IMAGING, KILLING, PHOTODYNAMIC THERAPY AND ANTIBIOTICS SCREENING, AND THEIR METHODS OF MANUFACTURING THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-05-26 WO disclosed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
US-20130109506-A1 GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT ACUSHNET COMPANY (US) 2013-05-02 US disclosed
EP-0790968-A1 IMPROVED BROMINATION PROCESS ALBEMARLE CORPORATION (US) 1997-08-27 EP disclosed
EP-0781262-A1 IMPROVED BROMINATION PROCESS ALBEMARLE CORPORATION (US) 1997-07-02 EP disclosed
WO-1996015087-A1 IMPROVED BROMINATION PROCESS ALBEMARLE CORPORATION (US) 1996-05-23 WO disclosed
WO-1996008457-A1 IMPROVED BROMINATION PROCESS ALBEMARLE CORPORATION (US) 1996-03-21 WO disclosed
EP-0502333-A1 Bromination process ALBEMARLE CORPORATION (US) 1992-09-09 EP disclosed
EP-0490378-A1 Bromination process ALBEMARLE CORPORATION (US) 1992-06-17 EP disclosed
US-5055235-A Heating non-condensed ring polyaromatics in the presence of bromine and a halogenation catalyst ETHYL CORPORATION (US) 1991-10-08 US disclosed