Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532061 | 1.00 | EPHX2 (0.43) | EPHX2FAAHTRPV1SPHK2SPHK1 | |
| SCHEMBL20590751 | 0.89 | DNM1 (0.48) | DNM1 | |
| Hydrochloric Acid SCHEMBL29286816 | 0.87 | DNM1 (0.50) | DNM1 | |
| SCHEMBL25219271 | 0.76 | EPHX2 (0.44) | EPHX2FAAHTRPV1GMNNUSP2 | |
| SCHEMBL8345479 | 0.74 | DNM1 (0.71) | EPHX2FAAHTRPV1DNM1GMNN | |
| SCHEMBL22063799 | 0.74 | FAAH (0.54) | EPHX2FAAHTRPV1DNM1GMNN | |
| SCHEMBL1333273 | 0.74 | DNM1 (0.71) | EPHX2FAAHTRPV1DNM1GMNN | |
| SCHEMBL21240011 | 0.74 | DNM1 (0.71) | EPHX2FAAHTRPV1DNM1GMNN | |
| SCHEMBL165446 | 0.74 | DNM1 (0.71) | EPHX2FAAHTRPV1DNM1GMNN | |
| SCHEMBL23606003 | 0.74 | FAAH (0.54) | EPHX2FAAHTRPV1DNM1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499790-B1 | THICKENED ACID COMPOSITIONS AND USES THEREOF | AKZO NOBEL NV (NL) | 2005-11-16 | — | — | EP | claimed |