Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 8/20 | 0.47 |
| ▸ | CD44 | P16070 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26684155 | 0.79 | HTR6 (0.49) | HTR6PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL1997957 | 0.78 | CYP11B2 (0.44) | SLC6A2SLC6A4SLC6A3PARP1 | |
| SCHEMBL24405379 | 0.75 | HTR6 (0.48) | HTR6PNMTCD44MAOBADRA2A | |
| SCHEMBL31152023 | 0.75 | PNMT (0.44) | HTR6PNMTCD44MAOBADRA2A | |
| SCHEMBL22144445 | 0.73 | DDB1 (0.46) | HTR6PNMTCD44MAOBADRA2A | |
| SCHEMBL20929543 | 0.71 | HTR6 (0.55) | HTR6SLC6A2SLC6A4SLC6A3PNMT | |
| Hydrochloric Acid SCHEMBL20703982 | 0.70 | HTR6 (0.46) | HTR6PNMTCD44MAOBPARP1 | |
| Hydrochloric Acid SCHEMBL30561540 | 0.70 | HTR6 (0.46) | HTR6PNMTCD44MAOBPARP1 | |
| SCHEMBL30450133 | 0.70 | DDB1 (0.53) | HTR6PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL26684149 | 0.70 | DDB1 (0.53) | HTR6PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |