Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16829583 | 0.84 | HTR2C (0.57) | HTR2C | |
| SCHEMBL1668725 | 0.81 | NAAA (0.49) | JAK3ALDH1A1 | |
| SCHEMBL5522132 | 0.79 | CHRM4 (0.45) | EPHX1 | |
| SCHEMBL1668790 | 0.79 | HTR2C (0.51) | HTR2CJAK3 | |
| SCHEMBL4765094 | 0.77 | ACHE (0.60) | HTR2C | |
| SCHEMBL27741863 | 0.77 | HTR2C (0.57) | HTR2C | |
| SCHEMBL301842 | 0.77 | BRD4 (0.47) | HTR2CALDH1A1 | |
| Acetic Acid SCHEMBL973925 | 0.76 | BRD4 (0.45) | HTR2CJAK3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2034724 | 0.76 | BRD4 (0.46) | HTR2CALDH1A1 | |
| SCHEMBL30014918 | 0.76 | MMP1 (0.61) | JAK3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186103-A1 | Substituted alkyl amido piperidines | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186103-A1 | Substituted alkyl amido piperidines | MCHR1, MCHR2, MC1R | HTR2C 32/4885EPHX1 2717/4885JAK3 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.