Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315804 | 0.89 | LMNA (0.52) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL7870569 | 0.84 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1HTTNR4A2LMNA | |
| SCHEMBL6046682 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HTTLMNATSHRHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28090259 | 0.83 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTNR4A2LMNA | |
| SCHEMBL3540201 | 0.83 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTNR4A2LMNA | |
| SCHEMBL3184374 | 0.83 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HTTNR4A2LMNA | |
| SCHEMBL12174317 | 0.83 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTNR4A2LMNA | |
| SCHEMBL4739763 | 0.83 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTNR4A2LMNA | |
| SCHEMBL25362705 | 0.81 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1HTTLMNATSHR | |
| SCHEMBL5988902 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HTTLMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040192956-A1 | Synthesis of 2-chloromethyl-6-methylbenzoic ester | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192956-A1 | Synthesis of 2-chloromethyl-6-methylbenzoic ester | PPARA, PPARG, PPARD | ALDH1A1 355/4885L3MBTL1 2800/4885HTT 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.