Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28090259

CCc1c(C)cccc1C(=O)OC.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
HTT P42858 2/20 0.47
NR4A2 P43354 1/20 0.46
TSHR P16473 2/20 0.46
LMNA P02545 2/20 0.46
HSD17B10 Q99714 2/20 0.44
CFTR P13569 1/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 6/20 0.43
MAPT P10636 2/20 0.43
PKM P14618 1/20 0.43
MAPK1 P28482 1/20 0.43
POLB P06746 3/20 0.43
ATM Q13315 1/20 0.43
GAA P10253 1/20 0.43
MYC P01106 1/20 0.42
GLA P06280 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7870569 0.98 ALDH1A1 (0.48) ALDH1A1L3MBTL1HTTNR4A2TSHR
SCHEMBL4739763 0.97 ALDH1A1 (0.47) ALDH1A1L3MBTL1HTTNR4A2TSHR
SCHEMBL22481057 0.87 LMNA (0.53) ALDH1A1HTTTSHRLMNAHSD17B10
SCHEMBL7428925 0.84 TSHR (0.63) ALDH1A1TSHRHSD17B10KMT2AKDM4E
SCHEMBL28680548 0.84 ALDH1A1 (0.53) ALDH1A1L3MBTL1HTTTSHRLMNA
SCHEMBL20161944 0.83 CXCR5 (0.47) ALDH1A1L3MBTL1HTTNR4A2TSHR
SCHEMBL6534556 0.83 ALDH1A1 (0.47) ALDH1A1L3MBTL1HTTNR4A2TSHR
SCHEMBL3184374 0.83 ALDH1A1 (0.50) ALDH1A1L3MBTL1HTTNR4A2TSHR
SCHEMBL12174317 0.83 ALDH1A1 (0.47) ALDH1A1L3MBTL1HTTNR4A2TSHR
SCHEMBL3540201 0.83 ALDH1A1 (0.47) ALDH1A1L3MBTL1HTTNR4A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104334629-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2016-08-24 CN disclosed