Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | REN | P00797 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP9 | P55211 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 2/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416814 | 0.95 | ALDH1A1 (0.62) | TSHRCASP3ALDH1A1THRBCYP2C9 | |
| SCHEMBL8612642 | 0.92 | ECE1 (0.64) | CASP3CASP7RENCASP1CASP9 | |
| SCHEMBL28252140 | 0.92 | ECE1 (0.64) | CASP3CASP7RENCASP1CASP9 | |
| SCHEMBL8588834 | 0.91 | ALDH1A1 (0.55) | TSHRCASP3CASP7RENALDH1A1 | |
| SCHEMBL6271137 | 0.91 | CASP3 (0.64) | CASP3CASP7RENCASP1CASP9 | |
| SCHEMBL22413453 | 0.90 | CASP3 (0.58) | TSHRCASP3CASP7RENCASP1 | |
| SCHEMBL11211146 | 0.89 | TSHR (0.57) | TSHRALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL28607135 | 0.89 | CASP3 (0.59) | CASP3CASP7RENCASP1CASP9 | |
| SCHEMBL28607136 | 0.89 | CASP3 (0.59) | CASP3CASP7RENCASP1CASP9 | |
| SCHEMBL2402461 | 0.88 | ALDH1A1 (0.67) | TSHRALDH1A1THRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828847-A4 | ENZYME CATALYSIS IN ORGANIC SOLUTIONS | BIOTECHNOLOGY RES & DEV (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6171813-B1 | MIXING CATALYST OF ENZYME-SURFACTANT ION PAIR COMPLEX WITH ORGANIC REACTION SOLVENT INCLUDING WATER FROM 0.03 TO 2.5% V/V; WATER INCREASES RATE OF CATALYSIS AND STABILIZES ENZYME WITHOUT INCREASING RATE OF HYDROLYSIS; PEPTIDE SYNTHESIS | BIOTECHNOLOGY RESEARCH & DEVELOP. CORP. | 2001-01-09 | — | — | US | disclosed |
| EP-0828847-A1 | ENZYME CATALYSIS IN ORGANIC SOLUTIONS | BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION (US) | 1998-03-18 | — | — | EP | disclosed |
| US-5719039-A | FOR PEPTIDE SYNTHESIS FROM ACYL DONORS AND NUCLEOPHILES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-02-17 | — | — | US | disclosed |
| WO-1996038577-A1 | ENZYME CATALYSIS IN ORGANIC SOLUTIONS | BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORP. (US) | 1996-12-05 | — | — | WO | disclosed |