Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | ECE1 | P42892 | 5/20 | 0.63 |
| ▸ | MME | P08473 | 4/20 | 0.63 |
| ▸ | CASP1 | P29466 | 2/20 | 0.60 |
| ▸ | CASP9 | P55211 | 1/20 | 0.60 |
| ▸ | REN | P00797 | 1/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252140 | 0.99 | ECE1 (0.64) | CASP3CASP7ECE1MMECASP1 | |
| SCHEMBL8612642 | 0.99 | ECE1 (0.64) | CASP3CASP7ECE1MMECASP1 | |
| SCHEMBL25287172 | 0.94 | ECE1 (0.61) | CASP3CASP7ECE1MMECTSD | |
| SCHEMBL3058668 | 0.94 | ECE1 (0.61) | CASP3CASP7ECE1MMECTSD | |
| SCHEMBL6534667 | 0.91 | TSHR (0.62) | CASP3CASP7ECE1MMECASP1 | |
| SCHEMBL22413453 | 0.90 | CASP3 (0.58) | CASP3CASP7ECE1MMECASP1 | |
| SCHEMBL8588907 | 0.90 | F2 (0.55) | CASP3CASP7ECE1MMECTSD | |
| SCHEMBL31607495 | 0.90 | CTSK (0.60) | CASP3CASP7ECE1MMECASP1 | |
| SCHEMBL8585984 | 0.90 | ECE1 (0.57) | CASP3CASP7ECE1MMECTSD | |
| SCHEMBL8492505 | 0.89 | MME (0.64) | ECE1MMECTSDACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005106025-A1 | METABOLIC TEST | PML APPLICATIONS LTD. (GB) | 2005-11-10 | — | — | WO | disclosed |