Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 8/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 3/20 | 0.33 |
| ▸ | ARG2 | P78540 | 3/20 | 0.33 |
| ▸ | PPIP5K2 | O43314 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 5/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | EYA2 | O00167 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL726303 | 0.95 | MLYCD (0.36) | MLYCDFAAHARG1ARG2PPIP5K2 | |
| Trifluoroacetic Acid SCHEMBL3708678 | 0.95 | MLYCD (0.36) | MLYCDFAAHARG1ARG2PPIP5K2 | |
| Trifluoroacetic Acid SCHEMBL3708677 | 0.95 | MLYCD (0.36) | MLYCDFAAHARG1ARG2PPIP5K2 | |
| Trifluoroacetic Acid SCHEMBL29024974 | 0.92 | MLYCD (0.35) | MLYCDFAAHARG1ARG2PPIP5K2 | |
| Trifluoroacetic Acid SCHEMBL6534970 | 0.91 | FAAH (0.47) | FAAHFUCA1CES1CES2MEN1 | |
| Trifluoroacetic Acid SCHEMBL7929496 | 0.90 | MLYCD (0.34) | MLYCDFAAHARG1ARG2PPIP5K2 | |
| Trifluoroacetic Acid SCHEMBL3794549 | 0.87 | FAAH (0.40) | FAAHFUCA1CES1CES2MEN1 | |
| Trifluoroacetic Acid SCHEMBL30324569 | 0.87 | FAAH (0.40) | FAAHFUCA1CES1CES2MEN1 | |
| Trifluoroacetic Acid SCHEMBL281599 | 0.87 | FAAH (0.40) | FAAHFUCA1CES1CES2MEN1 | |
| Trifluoroacetic Acid SCHEMBL28824297 | 0.84 | FAAH (0.41) | FAAHFUCA1CES1CES2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111323493-A | Method for detecting enantiomer of posaconazole starting material | 武汉赛沃医药科技有限公司 | 2020-06-23 | — | — | CN | claimed |
| CN-111323493-A | Method for detecting enantiomer of posaconazole starting material | 武汉赛沃医药科技有限公司 | 2020-06-23 | — | — | CN | disclosed |
| EP-0975560-A4 | CHIRAL SEPARATIONS OF AMINO ACIDS | CHIRAL TECHNOLOGIES INC (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-0975560-A1 | CHIRAL SEPARATIONS OF AMINO ACIDS | Chiral Technologies, Inc. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998041489-A1 | CHIRAL SEPARATIONS OF AMINO ACIDS | CHIRAL TECHNOLOGIES, INC. (US) | 1998-09-24 | — | — | WO | disclosed |