SCHEMBL6534893

SCHEMBL6534893

CCCCCCCCc1c(C(N)=O)ccc(C(N)=O)c1CCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ADRA2A P08913 3/20 0.50
SLC6A3 Q01959 3/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 2/20 0.50
CHRM2 P08172 2/20 0.50
CYP3A4 P08684 2/20 0.50
NR1I2 O75469 1/20 0.50
OPRK1 P41145 1/20 0.50
HTR2B P41595 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
PPARA Q07869 2/20 0.46
RARB P10826 5/20 0.45
APAF1 O14727 1/20 0.45
RGS12 O14924 1/20 0.45
HSP90AA1 P07900 1/20 0.45
MAPK1 P28482 1/20 0.45
PLK1 P53350 1/20 0.43
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1049187 1.00 MEN1 (0.50) MEN1KMT2AADRA2ASLC6A3MAPT
SCHEMBL27265024 1.00 MEN1 (0.50) MEN1KMT2AADRA2ASLC6A3MAPT
SCHEMBL29074022 1.00 MEN1 (0.50) MEN1KMT2AADRA2ASLC6A3MAPT
SCHEMBL8780461 1.00 MEN1 (0.50) MEN1KMT2AADRA2ASLC6A3MAPT
SCHEMBL8780464 0.93 PPARA (0.53) MEN1KMT2AADRA2ASLC6A3MAPT
SCHEMBL31186255 0.93 PPARA (0.53) MEN1KMT2AADRA2ASLC6A3MAPT
SCHEMBL28436765 0.93 MEN1 (0.45) MEN1KMT2AADRA2ASLC6A3MAPT
SCHEMBL9781027 0.92 MEN1 (0.45) MEN1KMT2AADRA2ASLC6A3MAPT
SCHEMBL6535320 0.89 LMNA (0.55) MEN1KMT2AADRA2ASLC6A3MAPT
SCHEMBL27405674 0.89 LMNA (0.55) MEN1KMT2AADRA2ASLC6A3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1099137-A4 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEM CO (US) 2004-10-06 EP claimed
EP-1099137-A1 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 2001-05-16 EP claimed
WO-1999061955-A1 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 1999-12-02 WO claimed