Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL16208245 | 0.83 | LMNA (0.55) | LMNAALDH1A1AKR1B1PPARGPPARD | |
| Butyric Acid SCHEMBL8820913 | 0.83 | FFAR3 (0.59) | LMNAALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL21768046 | 0.83 | LMNA (0.55) | LMNASLC15A2ALDH1A1FFAR3HDAC3 | |
| Acetic Acid SCHEMBL23907968 | 0.82 | LMNA (0.67) | LMNAALDH1A1GABRPGABRDGABRA1 | |
| Acetic Acid SCHEMBL222953 | 0.82 | LMNA (0.67) | LMNAALDH1A1GABRPGABRDGABRA1 | |
| Sebacic Acid SCHEMBL11757616 | 0.81 | GPR84 (0.54) | LMNAALDH1A1AKR1B1PPARGPPARD | |
| SCHEMBL27986820 | 0.81 | LMNA (0.52) | LMNASLC15A2ALDH1A1TSHRTDP1 | |
| SCHEMBL28843407 | 0.81 | LMNA (0.52) | LMNAALDH1A1EGLN1GABRPGABRD | |
| SCHEMBL11520475 | 0.80 | LMNA (0.46) | LMNASLC15A2ALDH1A1TSHR | |
| SCHEMBL21436753 | 0.80 | LMNA (0.46) | LMNAALDH1A1CYP1A2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038018-A4 | ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES | SCRIPPS RESEARCH INST (US) | 2004-10-13 | — | — | EP | disclosed |
| US-6589766-B1 | Use to catalyze ketone-ketone, ketone-aldehyde, aldehyde-ketone, and aldehyde-aldehyde intermolecular aldol reactions, and in some cases to catalyze their subsequent dehydration to yield aldol condensation products | THE SCRIPPS RESEARCH INSTITUTE | 2003-07-08 | — | — | US | disclosed |
| US-6326176-B1 | ALDOL CONDENSATIONS AND CATALYTIC ANTIBODIES | THE SCRIPPS RESEARCH INSTITUTE | 2001-12-04 | — | — | US | disclosed |
| EP-1038018-A1 | ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES | The Scripps Research Institute (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999031263-A1 | ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-06-24 | — | — | WO | disclosed |
| US-4710566-A | Purification of the messenger RNA cap-binding protein | YALE UNIVERSITY (US) | 1987-12-01 | — | — | US | disclosed |