Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13306594 | 1.00 | KMT2A (0.50) | KMT2AALDH1A1MAPTMEN1RXFP1 | |
| SCHEMBL6535359 | 0.85 | DHODH (0.54) | KMT2AALDH1A1MAPTMEN1HPGD | |
| SCHEMBL18880072 | 0.78 | ALDH1A1 (0.73) | KMT2AALDH1A1MAPTMEN1RXFP1 | |
| SCHEMBL21935482 | 0.78 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPTMEN1RXFP1 | |
| SCHEMBL103862 | 0.77 | KMT2A (0.61) | KMT2AALDH1A1MAPTMEN1RXFP1 | |
| SCHEMBL13390897 | 0.75 | KMT2A (0.63) | KMT2AALDH1A1MAPTMEN1RXFP1 | |
| SCHEMBL7517494 | 0.75 | KMT2A (0.54) | KMT2AALDH1A1MAPTMEN1RXFP1 | |
| SCHEMBL9891809 | 0.75 | TSHR (0.66) | KMT2AALDH1A1MAPTMEN1RXFP1 | |
| SCHEMBL15978829 | 0.74 | KMT2A (0.58) | KMT2AALDH1A1MAPTMEN1RXFP1 | |
| SCHEMBL13408812 | 0.73 | KMT2A (0.53) | KMT2AALDH1A1MAPTMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038018-A4 | ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES | SCRIPPS RESEARCH INST (US) | 2004-10-13 | — | — | EP | disclosed |
| US-6589766-B1 | Use to catalyze ketone-ketone, ketone-aldehyde, aldehyde-ketone, and aldehyde-aldehyde intermolecular aldol reactions, and in some cases to catalyze their subsequent dehydration to yield aldol condensation products | THE SCRIPPS RESEARCH INSTITUTE | 2003-07-08 | — | — | US | disclosed |
| US-6326176-B1 | ALDOL CONDENSATIONS AND CATALYTIC ANTIBODIES | THE SCRIPPS RESEARCH INSTITUTE | 2001-12-04 | — | — | US | disclosed |
| EP-1038018-A1 | ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES | The Scripps Research Institute (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999031263-A1 | ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-06-24 | — | — | WO | disclosed |