Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21935483 | 0.88 | MEN1 (0.37) | ALDH1A1KMT2AMAPTMEN1NPSR1 | |
| SCHEMBL25409652 | 0.79 | LMNA (0.40) | KMT2AMAPTMEN1NPSR1RAB9A | |
| SCHEMBL25409646 | 0.79 | LMNA (0.40) | KMT2AMAPTMEN1NPSR1RAB9A | |
| SCHEMBL13306594 | 0.78 | KMT2A (0.50) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL6535180 | 0.78 | KMT2A (0.50) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL18880072 | 0.76 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL19896651 | 0.76 | TAAR1 (0.39) | ALDH1A1SMN1; SMN2CYP2C9L3MBTL1KDM4E | |
| SCHEMBL103862 | 0.75 | KMT2A (0.61) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL14072820 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL9891809 | 0.72 | TSHR (0.66) | ALDH1A1KMT2AMAPTMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241501-B2 | Anticancer prodrug for overcoming drug resistance | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2022-02-08 | — | — | US | disclosed |
| US-20200129626-A1 | ANTICANCER PRODRUG FOR OVERCOMING DRUG RESISTANCE | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11241501-B2 | Anticancer prodrug for overcoming drug resistance | PDK2, PDK3, PDK1 | ALDH1A1 521/4885KMT2A 1988/4885MAPT 2816/4885 |
| US-20200129626-A1 | ANTICANCER PRODRUG FOR OVERCOMING DRUG RESISTANCE | PDK2, PDK3, PDK1 | ALDH1A1 521/4885KMT2A 1988/4885MAPT 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.