Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | STK10 | O94804 | 2/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535277 | 0.89 | ALDH1A1 (0.38) | RAPGEF4HTTALDH1A1CYP2C9HPGD | |
| SCHEMBL6535472 | 0.88 | ALDH1A1 (0.34) | RAPGEF4PRKCBHTTALDH1A1CYP2C9 | |
| SCHEMBL7774002 | 0.84 | ALDH1A1 (0.34) | THRBHTTALDH1A1CYP2C9HPGD | |
| SCHEMBL6882234 | 0.82 | HPGD (0.34) | HTTALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL15056135 | 0.82 | HPGD (0.37) | HTTALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL5681921 | 0.81 | ALDH1A1 (0.34) | ALDH1A1CYP2C9HPGDALOX15ALOX12 | |
| SCHEMBL10772026 | 0.81 | ALDH1A1 (0.34) | ALDH1A1CYP2C9HPGDALOX15ALOX12 | |
| SCHEMBL4750113 | 0.80 | ALDH1A1 (0.36) | HTTALDH1A1CYP2C9HPGDALOX15 | |
| SCHEMBL5153740 | 0.80 | RAPGEF4 (0.36) | RAPGEF4HTTALDH1A1CYP2C9HPGD | |
| SCHEMBL9009110 | 0.80 | ALDH1A1 (0.32) | RAPGEF4PRKCBALDH1A1CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622858-A2 | HEAT SENSITIVE RECORDING MATERIAL | Ciba SC Holding AG (CH) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004099116-A2 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |