SCHEMBL653535

SCHEMBL653535

O=C(CCCl)c1ccc(Cl)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.68
ERCC5 P28715 1/20 0.53
FEN1 P39748 1/20 0.53
KMT2A Q03164 4/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
MEN1 O00255 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
MAPT P10636 4/20 0.52
L3MBTL1 Q9Y468 4/20 0.52
HSD11B1 P28845 1/20 0.51
ALDH1A1 P00352 2/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
MMP1 P03956 1/20 0.50
HPGD P15428 1/20 0.50
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9712507 1.00 GSK3B (0.68) GSK3BERCC5FEN1KMT2ANPC1
SCHEMBL10972806 0.94 GSK3B (0.61) GSK3BERCC5FEN1KMT2ANPC1
SCHEMBL11149859 0.89 MMP1 (0.67) GSK3BERCC5FEN1KMT2ANPC1
SCHEMBL16552727 0.88 GSK3B (0.70) GSK3BERCC5FEN1KMT2ANPC1
SCHEMBL2235019 0.87 GSK3B (0.63) GSK3BERCC5FEN1KMT2ANPC1
SCHEMBL5660844 0.85 GSK3B (0.61) GSK3BERCC5FEN1KMT2ANPC1
SCHEMBL5660040 0.84 GSK3B (0.59) GSK3BERCC5FEN1KMT2ANPC1
SCHEMBL5662338 0.84 GSK3B (0.59) GSK3BERCC5FEN1KMT2ANPC1
SCHEMBL27570052 0.82 GSK3B (0.57) GSK3BERCC5FEN1KMT2ANPC1
SCHEMBL8750790 0.82 L3MBTL1 (0.65) GSK3BERCC5FEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250042831-A1 PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE ADAMA MAKHTESHIM LTD. (IL) 2025-02-06 US claimed
EP-4444690-A1 PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE ADAMA MAKHTESHIM LTD. (IL) 2024-10-16 EP claimed
CN-118591521-A Process for preparing 5-chloro-2, 3-dihydro-1H-inden-1-one 安道麦马克西姆有限公司 2024-09-03 CN claimed
WO-2023102721-A1 PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE ADAMA MAKHTESHIM LTD. (IL) 2023-06-15 WO claimed
CN-115436507-A Method for detecting content of 3,4' -dichloropropiophenone 山东京博生物科技有限公司 2022-12-06 CN claimed
CN-111454137-B Synthetic method for improving yield of 5-chloro-1-indanone 山东京博生物科技有限公司 2022-09-23 CN claimed
CN-112939756-B Improved process for preparing 5-chloro-indanone 上海鼎素精细化工有限公司 2022-07-08 CN claimed
CN-112939756-A Improved process for preparing 5-chloro-indanone 上海鼎素精细化工有限公司 2021-06-11 CN claimed
CN-111454137-A Synthetic method for improving yield of 5-chloro-1-indanone 山东京博生物科技有限公司 2020-07-28 CN claimed
CN-111205175-A Synthetic method for improving yield of 5-chloro-1-indanone 京博农化科技有限公司 2020-05-29 CN claimed
WO-2000043342-A1 METHOD FOR PRODUCING A INDANONE OR THIOINDANONE TYPE COMPOUND RHODIA CHIMIE (FR) 2000-07-27 WO claimed
EP-0800500-B1 A PROCESS FOR PREPARING 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE DU PONT (US) 1999-06-02 EP claimed
US-5811585-A CONTACTING 3-CHLORO-1-/4-CHLOROPHENYL/-1-PROPANOL WITH ACID CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-09-22 US claimed
EP-0800500-A1 A PROCESS FOR PREPARING 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-10-15 EP claimed
WO-1996020151-A1 A PROCESS FOR PREPARING 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-04 WO claimed
EP-0111863-B1 PROCESS FOR THE PRODUCTION OF BETA,4-DICHLORO-PROPIOPHENONE BAYER AG (DE) 1985-08-07 EP claimed
US-20250042831-A1 PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE ADAMA MAKHTESHIM LTD. (IL) 2025-02-06 US disclosed
EP-4444690-A1 PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE ADAMA MAKHTESHIM LTD. (IL) 2024-10-16 EP disclosed
US-4017631-A MICROBIOCIDES JANSSEN PHARMACEUTICA N.V. (BE) 1977-04-12 US disclosed
US-3991202-A ANTIMICROBIALS JANSSEN PHARMACEUTICA N.V. (BE) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042831-A1 PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE SI, IDO1, CYP4B1 GSK3B 1400/4885ERCC5 1300/4885FEN1 2696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.