Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535242 | 1.00 | KMT2A (0.50) | KMT2AMEN1APPFBP1PTGS2 | |
| SCHEMBL22076572 | 0.87 | MAOB (0.49) | KMT2AMEN1APPFBP1PTGS2 | |
| SCHEMBL22113522 | 0.85 | PTGS2 (0.59) | KMT2AMEN1APPPTGS2MAOB | |
| SCHEMBL13597788 | 0.77 | APP (0.60) | KMT2AMEN1APPFBP1PTGS2 | |
| SCHEMBL6535101 | 0.76 | HSD17B3 (0.56) | APPMAOBMAOAPTGS1MAPT | |
| SCHEMBL13306343 | 0.76 | MEN1 (0.52) | KMT2AMEN1APPFBP1PTGS2 | |
| SCHEMBL13306592 | 0.76 | HSD17B3 (0.56) | APPMAOBMAOAPTGS1MAPT | |
| SCHEMBL27277382 | 0.75 | MEN1 (0.55) | KMT2AMEN1APPFBP1PTGS2 | |
| SCHEMBL9411953 | 0.74 | APP (0.51) | KMT2AMEN1APPFBP1PTGS2 | |
| SCHEMBL9411956 | 0.74 | APP (0.51) | KMT2AMEN1APPFBP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038018-A4 | ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES | SCRIPPS RESEARCH INST (US) | 2004-10-13 | — | — | EP | disclosed |
| US-6589766-B1 | Use to catalyze ketone-ketone, ketone-aldehyde, aldehyde-ketone, and aldehyde-aldehyde intermolecular aldol reactions, and in some cases to catalyze their subsequent dehydration to yield aldol condensation products | THE SCRIPPS RESEARCH INSTITUTE | 2003-07-08 | — | — | US | disclosed |
| US-6326176-B1 | ALDOL CONDENSATIONS AND CATALYTIC ANTIBODIES | THE SCRIPPS RESEARCH INSTITUTE | 2001-12-04 | — | — | US | disclosed |
| EP-1038018-A1 | ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES | The Scripps Research Institute (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999031263-A1 | ALDOL CONDENSATIONS BY CATALYTIC ANTIBODIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-06-24 | — | — | WO | disclosed |