Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535242 | 0.87 | KMT2A (0.50) | MAOBBCHEAPPMEN1KMT2A | |
| SCHEMBL6535451 | 0.87 | KMT2A (0.50) | MAOBBCHEAPPMEN1KMT2A | |
| SCHEMBL22113522 | 0.83 | PTGS2 (0.59) | MAOBAPPMEN1KMT2APTGS2 | |
| SCHEMBL8885832 | 0.79 | PAM (0.50) | MAOBBCHECYP1B1MAPT | |
| SCHEMBL16859620 | 0.78 | CYP1A2 (0.47) | MAOBMEN1KMT2AGRIK1GRIK2 | |
| SCHEMBL16859619 | 0.78 | CYP1A2 (0.47) | MAOBMEN1KMT2AGRIK1GRIK2 | |
| SCHEMBL4914085 | 0.74 | PAM (0.59) | MAOBBCHEAPPMEN1KMT2A | |
| SCHEMBL4632485 | 0.74 | MAOB (0.54) | MAOBBCHEAPPMEN1KMT2A | |
| SCHEMBL4632486 | 0.74 | MAOB (0.54) | MAOBBCHEAPPMEN1KMT2A | |
| SCHEMBL3103681 | 0.73 | GRIK1 (0.68) | MAOBBCHEAPPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10906860-B2 | Method for synthesizing chiral beta-hydroxy acid ester compound | WENZHOU UNIVERSITY (CN) | 2021-02-02 | — | — | US | disclosed |
| US-20200190013-A1 | METHOD FOR SYNTHESIZING CHIRAL BETA-HYDROXY ACID ESTER COMPOUND | WENZHOU UNIVERSITY (CN) | 2020-06-18 | — | — | US | disclosed |
| CN-109734600-A | A kind of synthetic method of chiral beta carboxylic acid ester type compound | 温州大学 | 2019-05-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190013-A1 | METHOD FOR SYNTHESIZING CHIRAL BETA-HYDROXY ACID ESTER COMPOUND | HSD11B1, HACL2, HAAO | MAOB 1306/4885BCHE 442/4885APP 328/4885 |
| US-10906860-B2 | Method for synthesizing chiral beta-hydroxy acid ester compound | HSD11B1, HACL2, HAAO | MAOB 1306/4885BCHE 442/4885APP 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.