Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440505 | 0.89 | TDP1 (0.47) | TDP1SMN1; SMN2L3MBTL1POLBRECQL | |
| SCHEMBL2350573 | 0.87 | KDM4E (0.55) | TDP1L3MBTL1POLBRECQLBLM | |
| SCHEMBL2350885 | 0.86 | MAPT (0.48) | TDP1SMN1; SMN2L3MBTL1POLBRECQL | |
| SCHEMBL7411536 | 0.85 | TDP1 (0.69) | TDP1SMN1; SMN2POLBNPC1PKM | |
| SCHEMBL8436420 | 0.79 | CFD (0.56) | TDP1L3MBTL1POLBRECQLBLM | |
| SCHEMBL15056471 | 0.78 | TDP1 (0.50) | TDP1SMN1; SMN2NPC1PKMRAB9A | |
| SCHEMBL22200953 | 0.78 | SMN1; SMN2 (0.55) | TDP1SMN1; SMN2L3MBTL1POLBRECQL | |
| SCHEMBL8437783 | 0.78 | TDP1 (0.47) | TDP1SMN1; SMN2L3MBTL1POLBRECQL | |
| SCHEMBL8437822 | 0.78 | TDP1 (0.47) | TDP1SMN1; SMN2L3MBTL1POLBRECQL | |
| SCHEMBL28190954 | 0.76 | IMPDH2 (0.63) | TDP1SMN1; SMN2L3MBTL1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368390-A4 | HIGH MOLECULAR WEIGHT POLYMERS CONTAINING PENDANT SALICYLIC ACID GROUPS | ONDEO NALCO CO (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1368390-A1 | HIGH MOLECULAR WEIGHT POLYMERS CONTAINING PENDANT SALICYLIC ACID GROUPS | Ondeo Nalco Company (US) | 2003-12-10 | — | — | EP | disclosed |
| US-20030027964-A1 | High molecular weight polymers containing pendant salicylic acid groups | ONDEO NALCO COMPANY | 2003-02-06 | — | — | US | disclosed |
| WO-2002060966-A1 | HIGH MOLECULAR WEIGHT POLYMERS CONTAINING PENDANT SALICYLIC ACID GROUPS | ONDEO NALCO COMPANY (US) | 2002-08-08 | — | — | WO | disclosed |