Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | SGMS1 | Q86VZ5 | 3/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846298 | 0.84 | KMT2A (0.52) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL6535177 | 0.84 | KMT2A (0.55) | KMT2ACA12CA1CA2CA7 | |
| Bromide SCHEMBL3850333 | 0.82 | KMT2A (0.57) | KMT2ACA12CA1CA2CA7 | |
| Bromide SCHEMBL3845852 | 0.74 | KMT2A (0.54) | KMT2ACA12CA1CA2CA7 | |
| Bromide SCHEMBL8076842 | 0.71 | KMT2A (0.54) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL6766613 | 0.71 | SLC9A1 (0.47) | KMT2AMAPTPOLBNPSR1 | |
| Hydrochloric Acid SCHEMBL3851286 | 0.68 | KMT2A (0.50) | KMT2ACA12CA9MAPTMEN1 | |
| Bromide SCHEMBL3847295 | 0.67 | KMT2A (0.52) | KMT2AOPRM1OPRD1 | |
| SCHEMBL2989475 | 0.65 | MEN1 (0.61) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL4181492 | 0.62 | ALDH1A1 (0.72) | KMT2ACA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257272-A4 | THIAZOLIUM COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | ALTEON INC (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1257272-A1 | THIAZOLIUM COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | Alteon, Inc. (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001062250-A1 | THIAZOLIUM COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING | ALTEON, INC. (US) | 2001-08-30 | — | — | WO | disclosed |