SCHEMBL2989475

SCHEMBL2989475

CCC(=O)c1c(O)cccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
CYP3A4 P08684 1/20 0.61
PTGS1 P23219 1/20 0.61
DRD3 P35462 1/20 0.61
ALDH1A1 P00352 1/20 0.60
MAPT P10636 1/20 0.60
HTT P42858 1/20 0.60
ATM Q13315 1/20 0.60
CA9 Q16790 5/20 0.57
CA12 O43570 4/20 0.57
CA1 P00915 4/20 0.57
CA2 P00918 4/20 0.57
CA7 P43166 4/20 0.57
CA14 Q9ULX7 4/20 0.57
THRB P10828 1/20 0.56
PTPN1 P18031 3/20 0.51
ACHE P22303 2/20 0.46
SGMS1 Q86VZ5 2/20 0.46
SGMS2 Q8NHU3 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28283448 0.94 MEN1 (0.55) MEN1KMT2ACYP3A4PTGS1DRD3
SCHEMBL10158530 0.87 CA9 (0.55) MEN1KMT2ACYP3A4PTGS1DRD3
SCHEMBL10878661 0.87 CA9 (0.50) MEN1KMT2ACYP3A4PTGS1DRD3
SCHEMBL24451122 0.86 CA9 (0.48) MEN1KMT2ACYP3A4PTGS1DRD3
SCHEMBL12780415 0.86 CA9 (0.48) MEN1KMT2ACYP3A4PTGS1DRD3
SCHEMBL28206890 0.82 PTPN1 (0.57) KMT2ACYP3A4ALDH1A1MAPTHTT
SCHEMBL19605665 0.82 BID (0.55) MEN1KMT2AALDH1A1MAPTHTT
SCHEMBL28206869 0.82 ERN1 (0.50) MEN1KMT2ACYP3A4PTGS1DRD3
SCHEMBL4181492 0.82 ALDH1A1 (0.72) MEN1KMT2AALDH1A1MAPTHTT
SCHEMBL24450915 0.81 CA9 (0.44) MEN1KMT2ACYP3A4PTGS1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed
US-20250115597-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO LTD (CN) 2025-04-10 US disclosed
US-12129250-B2 TYK2 inhibitors and compositions and methods thereof LYNK PHARMACEUTICALS CO. LTD. (CN) 2024-10-29 US disclosed
EP-4448514-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF Lynk Pharmaceuticals Co. Ltd. (CN) 2024-10-23 EP disclosed
US-20240336868-A1 COMPOSITIONS COMPRISING ADAMANTYL ESTER-CONTAINING COMPOUNDS THE PROCTER & GAMBLE COMPANY 2024-10-10 US disclosed
CN-118401516-A TYK2 inhibitors, compositions and methods thereof 凌科药业(杭州)有限公司 2024-07-26 CN disclosed
US-20240124448-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO. LTD. (CN) 2024-04-18 US disclosed
WO-2023109954-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO. LTD. (CN) 2023-06-22 WO disclosed
US-20020025301-A1 Novel flavonoids and their use in cosmetic and dermatological preparations BASF AKTIENGESELLSCHAFT (DE) 2002-02-28 US disclosed
CN-1335309-A New eka-favone and its application in preparation of cosmetic and dermatology BASF AG (DE) 2002-02-13 CN disclosed
US-5432014-A Flat display element SANYO ELECTRIC CO., LTD. (JP) 1995-07-11 US disclosed
US-4906658-A Fluoro-sulfones MERCK FROSST CANADA, INC. (CA) 1990-03-06 US disclosed
EP-0331422-A2 Method of preparing 2-acylresorcinols MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-09-06 EP disclosed
EP-0288202-A2 Fluoro-sulfones MERCK FROSST CANADA INC. (CA) 1988-10-26 EP disclosed
US-3985783-A Process for ring acylation of phenols THE DOW CHEMICAL COMPANY (US) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020025301-A1 Novel flavonoids and their use in cosmetic and dermatological preparations CBR1, CYP1B1, CYP1A1 MEN1 1459/4885KMT2A 3461/4885CYP3A4 155/4885
US-20240124448-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF TYK2, JAK2, JAK1 MEN1 2298/4885KMT2A 242/4885CYP3A4 4272/4885
US-20250115597-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF TYK2, JAK2, JAK1 MEN1 2298/4885KMT2A 242/4885CYP3A4 4272/4885
US-12129250-B2 TYK2 inhibitors and compositions and methods thereof TYK2, JAK2, JAK1 MEN1 2298/4885KMT2A 242/4885CYP3A4 4272/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA MEN1 4119/4885KMT2A 1674/4885CYP3A4 3624/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA MEN1 4535/4885KMT2A 2789/4885CYP3A4 1140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.