SCHEMBL6535876

SCHEMBL6535876

CCCC(C)c1cc(O)cc(C(C)CCC)c1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 9/20 0.42
TSHR P16473 2/20 0.38
HIF1A Q16665 2/20 0.38
ADRA1A P35348 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
CYP3A4 P08684 2/20 0.34
PTGS2 P35354 1/20 0.34
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
CASP7 P55210 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916418 0.95 ADRB2 (0.46) ADRB2TSHRHIF1AADRA1AESR1
SCHEMBL5916413 0.83 ADRB2 (0.56) ADRB2TSHRHIF1AADRA1ACYP3A4
SCHEMBL6536206 0.81 ALOX15 (0.48) ADRB2TSHRHIF1AADRA1AESR1
SCHEMBL69048 0.81 ADRB2 (0.57) ADRB2TSHRHIF1AADRA1ACYP3A4
SCHEMBL11808633 0.79 ADRB2 (0.55) ADRB2TSHRHIF1AADRA1ACYP3A4
SCHEMBL11615908 0.79 ADRB2 (0.55) ADRB2TSHRHIF1AADRA1ACYP3A4
SCHEMBL11737358 0.79 ADRB2 (0.55) ADRB2TSHRHIF1AADRA1ACYP3A4
SCHEMBL68950 0.79 ADRB2 (0.55) ADRB2TSHRHIF1AADRA1ACYP3A4
SCHEMBL68546 0.79 ADRB2 (0.55) ADRB2TSHRHIF1AADRA1ACYP3A4
SCHEMBL6912280 0.79 ADRB1 (0.50) ADRB2TSHRHIF1AADRA1AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101189318-B Reversibly thermochromic compositions CIBA SC HOLDING AG 2012-06-20 CN disclosed
CN-101189318-A Reversibly thermochromic compositions CIBA SC HOLDING AG (CH) 2008-05-28 CN disclosed
EP-1358214-A4 THERMOSETTING RESIN-FIBER COMPOSITE AND METHOD AND APPARATUS FOR THE MANUFACTURE THEREOF CAPPI GIUSEPPI (US) 2004-08-18 EP disclosed
WO-2002070599-A9 THERMOSETTING RESIN-FIBER COMPOSITE AND METHOD AND APPARATUS FOR THE MANUFACTURE THEREOF CAPPI GIUSEPPI (US) 2004-07-22 WO disclosed
US-20040115459-A1 Thermosetting resin-fiber composite and method and apparatus for the manufacture thereof CAPPI GIUSEPPI (US) 2004-06-17 US disclosed
CN-1461311-A Thernosetting resin-fiber composite and method and apparatus for manufacture thereof PHENOLIC RESIN AG (DE) 2003-12-10 CN disclosed
EP-1358214-A2 THERMOSETTING RESIN-FIBER COMPOSITE AND METHOD AND APPARATUS FOR THE MANUFACTURE THEREOF Bakelite AG (DE) 2003-11-05 EP disclosed
WO-2002070599-A2 THERMOSETTING RESIN-FIBER COMPOSITE AND METHOD AND APPARATUS FOR THE MANUFACTURE THEREOF G.P. CONCEPTS LLC (US) 2002-09-12 WO disclosed
EP-0032062-B2 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
EP-0032062-B1 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-04-03 EP disclosed
EP-0032060-B1 NOVOLAK RESIN COMPOSITION AND PRODUCTS FORMED THEREFROM MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-10-24 EP disclosed
US-4345054-A High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-17 US disclosed
US-4342852-A Setting type resin composition containing a substantially linear, high-molecular-weight novolak substituted phenolic resin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-03 US disclosed
EP-0032062-A2 High-molecular-weight novolak substituted phenolic resins and their preparation MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-07-15 EP disclosed
EP-0032060-A2 Novolak resin composition and products formed therefrom MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-07-15 EP disclosed