Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536412 | 0.82 | — | — | |
| SCHEMBL6536023 | 0.74 | — | — | |
| SCHEMBL16143743 | 0.62 | ALDH1A1 (0.35) | ALDH1A1FABP7FABP5MAPK1L3MBTL1 | |
| Formic Acid Methyl Ester SCHEMBL28511174 | 0.56 | OPRM1 (0.49) | ALDH1A1MAPK1LMNA | |
| Hydroxyamine SCHEMBL27588656 | 0.55 | ALDH1A1 (0.48) | ALDH1A1MAPK1L3MBTL1LMNASLC1A3 | |
| SCHEMBL22394368 | 0.55 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1LMNAHPGD | |
| Phenol SCHEMBL27648750 | 0.55 | LMNA (0.54) | ALDH1A1MAPK1L3MBTL1LMNAHPGD | |
| Phenol SCHEMBL28213971 | 0.54 | LMNA (0.48) | ALDH1A1MAPK1L3MBTL1LMNASLC1A3 | |
| SCHEMBL5304631 | 0.54 | FNTA (0.53) | ALDH1A1MAPK1L3MBTL1LMNAMEN1 | |
| SCHEMBL23704793 | 0.53 | ALDH1A1 (0.39) | ALDH1A1SLC1A3SLC1A2SLC1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425015-A4 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1425015-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003015715-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |